Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | HCID 14996561 | HCID 14996561 | — |
| Solvent | Water | HCID 962 | — |
| Product | Cefadroxil | HCID 47965 | — |
Reaction Steps
Cefadroxil monomethylformamide solvate (30 g) prepared according to Example 3 was slurried in 150 ml of a mixture 1:1 of methanol and isopropyl alcohol with 1% of water at 52° C. After 70' at 52° C. the mixture was cooled to 10° C., filtered and washed with acetone to yield 23.5 g of substantially anhydrous crystalline cefadroxil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05329001 |
|---|
| Source dataset | uspto-grants-1994_07 |
|---|
| ORD ID | ord-b2c5d55da4c34785bbea002c921a8555 |
|---|
| Source note | uspto-grants-1994_07 |
|---|
