Triethylsilane → HCID 57043096, compound

Participants

Reaction Steps

438 mg of (1S, 2R)-2-benzoyl-1-methoxycarbonylcyclohex-4-ene was dissolved in 2.5 ml of trifluoroacetic acid. To the solution, 2.5 ml of triethylsilyl hydride (Et3SiH) was added at 50° C., and the solution was stirred for 30 minutes at the same temperature. After the solution was allowed to stand to return to room temperature, a saturated sodium bicarbonate solution was added, and the water layer was extracted with ether. Then, the organic layer was dried over anhydrous magnesium sulfate, concentrated, and the residure was subjected to silica gel column chromatography (ether:hexane=4:96), thereby obtaining 221 mg of the titled compound.

Provenance & Evidence