Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Reactant | Acetohydrazide | HCID 14039 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 96134-65-5 | HCID 13409712 | — |
Reaction Steps
A mixture of isatoic anhydride (16.3 g, 0.1 mol), p-toluenesulfonic acid (0.2 g, 1.1 mmol), glacial acetic acid (10 ml), acethydrazide (7.4 g, 0.1 mol) and dry toluene (90 ml) was stirred at 120° C. for 4 h, cooledto room temperature and poured into ice water. Toluene (500 ml) was added, and the phases were separated. The aqueous phase was extracted with CH2Cl2 (2×100 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05330990 |
|---|
| Source dataset | uspto-grants-1994_07 |
|---|
| ORD ID | ord-ffb816bf758d4ab3ae9d28fc55f06bf4 |
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| Source note | uspto-grants-1994_07 |
|---|
