HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Carboxymethyl)-5-methylbenzoic acid → 7-Methylisochroman-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Carboxymethyl)-5-methylbenzoic acid | HCID 12593129 | — |
| Solvent | Acetyl chloride | HCID 6367 | — |
| Product | 7-Methylisochroman-1,3-dione | HCID 45117217 | 95.3% |
Reaction Steps
To 100ml of acetyl chloride, 5.4 g of 4-methylhomophthalic acid was added and the resulting mixture was heated to reflux for 4 hours. The solvent was evaporated under reduced pressure and the generated crystals were washed with ether to obtain 4.67 g of 4-methylhomophthalic anhydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05330991 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-2716036d745642e598d010371f7c3d9a |
| Source note | uspto-grants-1994_07 |