Thiazolidinedione → HCID 54512542, compound

Participants

Reaction Steps

4-[(5-Methyl-2-phenyl-4-oxazolyl)methylaminocaronyl]benzaldehyde (0.880 g, 2.75 mmol), thiazolidine-2,4-dione (0.483 g, 4.12 mmol) and sodium acetate(0.676 g, 8.24 mmol) were intimately mixed and heated at 140°-145° C. for 45 minutes, then cooled to room temperature, the solids triturated and stirred with mL of water for 30 minutes and 1.20 g of present title product recovered by filtration; mp 235°-237° C. (dec); tlc Rf 0.2 (3:1 ethyl acetate:hexane).

Provenance & Evidence