Methanol → HCID 178499646, compound

Participants

Reaction Steps

A solution of 1H-indazole-3-acetic acid (1.0 g) in methanol (30 ml) containing five drops of concentrated sulfuric acid was refluxed for 8 hours. It was then concentrated to a low volume, diluted with ethyl acetate (20 ml). The organic layer washed with water (2×10 ml) and then with sodium bicarbonate solution (10 ml, 10%). The ethyl acetate layer was collected and then dried to obtain the title compound (yield: 0.8 g; m.p. 146° C.).

Provenance & Evidence