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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1729086Generated: November 2, 2026

Phenethylamine → phenylalaninol, (S)-

https://huagongshe.com/reaction/1729086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
Reactant2-adamantyl ChloroformateHCID 10878537—
Productphenylalaninol, (S)-HCID 447213—

Reaction Steps

The acid 6 is condensed with amines such as illustrated in Scheme X to produce final products, for example, condensation of 6 with phenylethylamine gives compound 13a with (S)-(-)-2-amino-3-phenyl-1-propanol gives compound 13b and with (R)-4-[[(2-amino-1-phenyl)ethyl]amino]-4-oxobutanoic acid benzyl ester to give 13c and 13d.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05331006
Source datasetuspto-grants-1994_07
ORD IDord-0e8c59d2332245d584583bb408c7978a
Source noteuspto-grants-1994_07