Dichloromethane → HCID 178476788, compound

HRID 1729187Notes

Reaction equation

HRID 1729187 reaction equation
C[Si](C)(C)Cl.[CH2:6]([O:8][P:9](C(OCC)(OCC)C)([CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:10])[CH3:7].ClCCl>C(O)C>[CH2:6]([O:8][PH:9]([CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:10])[CH3:7]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6397ChlorotrimethylsilaneHCID 117226951,1-Diethoxyethyl(cyclohexylmethyl)phosphinic acid ethyl ester

Product 1

HCID 178476788HCID 178476788, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

150 g of trimethylchlorosilane are added to a solution of 213 g of 1,1-diethoxyethyl(cyclohexylmethyl)phosphinic acid ethyl ester in 600 ml of a mixture of dichloromethane and ethanol (90:10% by volume) and the batch is stirred for 2 to 3 days at room temperature. The solvent is removed and the residue is distilled under reduced pressure to give P-(cyclohexylmethyl)phosphinic acid ethyl ester having a boiling point of 50° (2×10-4 mbar).

Workup

  1. customThe solvent is removed
  2. distillationthe residue is distilled under reduced pressure

Sources & evidence

ORD record
ord-2839062bf7ca4566abc42cac3dd7cdc6
Source dataset
uspto-grants-1994_07
Patent number
US05332729

Reaction notes

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