HCID 495677, compound → HCID 19011694, compound

HRID 1729214Notes

Reaction equation

HRID 1729214 reaction equation
OC1C[N:5](C(=O)C2C=CC3OCOC=3C=2)C(C(O)=O)C1.[OH:21][CH:22]1[CH2:26][N:25]([C:27](=[O:40])[C:28]2[CH:33]=[C:32]([O:34][CH3:35])[C:31]([O:36][CH3:37])=[C:30]([O:38][CH3:39])[CH:29]=2)[CH:24]([C:41]([OH:43])=O)[CH2:23]1>>[OH:21][CH:22]1[CH2:26][N:25]([C:27](=[O:40])[C:28]2[CH:33]=[C:32]([O:34][CH3:35])[C:31]([O:36][CH3:37])=[C:30]([O:38][CH3:39])[CH:29]=2)[CH:24]([C:41]([NH2:5])=[O:43])[CH2:23]1

Participants

3

Reactant 2

HCID 495677HCID 495677, compoundHCID 16771157HCID 16771157, compound

Product 1

HCID 19011694HCID 19011694, compoundYield 60%

Procedure

By carrying out the procedure as in Example 9, but replacing 4-hydroxy-1-(3,4-methylenedioxybenzoyl)pyrrolidine-2-carboxylic acid by the 4-hydroxy-1-(3,4,5-trimethoxybenzoyl)pyrrolidine-2-carboxylic acid obtained in Example 8, the title product is obtained.

Sources & evidence

ORD record
ord-90c1a3772bf943cd90eb4c6636e6b989
Source dataset
uspto-grants-1994_07
Patent number
US05332735

Reaction notes

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