HCID 16771157, compound → HCID 19011715, compound

HRID 1729216Notes

Reaction equation

HRID 1729216 reaction equation
[OH:1][CH:2]1[CH2:6][N:5]([C:7](=[O:17])[C:8]2[CH:13]=[CH:12][C:11]3[O:14][CH2:15]O[C:10]=3[CH:9]=2)[CH:4]([C:18]([OH:20])=[O:19])[CH2:3]1.O[CH:22]1CN(C(=O)C2C=CC(OC)=CC=2)C(C(O)=O)C1>>[OH:1][CH:2]1[CH2:6][N:5]([C:7](=[O:17])[C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=2)[CH:4]([C:18]([O:20][CH3:22])=[O:19])[CH2:3]1

Participants

3

Reactant 2

HCID 16771157HCID 16771157, compoundHCID 16774119HCID 16774119, compound

Product 1

HCID 19011715HCID 19011715, compoundYield 40%

Procedure

By carrying out the procedure as in Example 11, but replacing 4-hydroxy-1-(3,4-methylenedioxybenzoyl)pyrrolidine-2-carboxylic acid by the 4-hydroxy-1-(4-methoxy-benzoyl)pyrrolidine-2-carboxylic acid obtained in Example 57, the title product is obtained.

Sources & evidence

ORD record
ord-b3451fae370a4b92924496a71e7bf3ab
Source dataset
uspto-grants-1994_07
Patent number
US05332735

Reaction notes

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