HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → 1-[(3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy]-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | 2-{[(3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy]methyl}oxirane | HCID 15840415 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-[(3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy]-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-ol | HCID 3073900 | — |
Reaction Steps
140 mg (0.63 mmol) of the compound obtained in Step A are dissolved in 1.5 cm3 of anhydrous tetrahydrofuran. 600 mg (3.15 mmol) of 1-(2-methoxyphenyl)piperazine, diluted in 1.5 cm3 of anhydrous tetrahydrofuran, are added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05332741 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-448ea7be745046d1a0a3d42e3378b2f4 |
| Source note | uspto-grants-1994_07 |