Chlorosulfonic acid → HCID 22101224, compound

HRID 1729291Notes

Reaction equation

HRID 1729291 reaction equation
[O:1]([CH2:8][CH2:9][CH2:10][Br:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:12]([Cl:16])(=O)(=[O:14])[OH:13]>C(Cl)(Cl)Cl>[Br:11][CH2:10][CH2:9][CH2:8][O:1][C:2]1[CH:7]=[CH:6][C:5]([S:12]([Cl:16])(=[O:14])=[O:13])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24638Chlorosulfonic acidHCID 68522Benzene, (3-bromopropoxy)-

Product 1

HCID 22101224HCID 22101224, compoundYield 40%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Conditions

Temperature
-10 °C

Procedure

20 ml of a chloroform solution containing 5.8 g of 3-phenoxypropyl bromide was cooled to -10° C., and 3.6 ml of chlorosulfuric acid was added thereto, followed by stirring at room temperature for 1 hour. The reaction solution was poured onto ice, and extraction was performed with 100 ml of chloroform. Water washing, drying and concentration were successively carried out to obtain 3.4 g (yield: 40%)of 4-(3-bromopropoxy)benzenesulfonic acid chloride in an oily state.

Workup

  1. additionThe reaction solution was poured onto ice, and extraction
  2. dry with materialWater washing, drying
  3. concentrationconcentration

Sources & evidence

ORD record
ord-e8f503b1ee884cd3af1fc1ea02cd6cd9
Source dataset
uspto-grants-1994_07
Patent number
US05332739

Reaction notes

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