2-(Bromomethyl)benzonitrile → HCID 53974867, compound

Participants

Reaction Steps

A mixture of 2.57 g of 6-butyl-1-p-hydroxybenzyl-1,2-dihydro-2-oxopyridine (obtainable from IIIa and p-hydroxybenzyl bromide), 0.5 g of CH3ONa and 40 ml of DMSO is stirred for 0.5 hour. A solution of 2.2 g of o-cyanobenzyl bromide in 15 ml of DMSO is added dropwise and the mixture is stirred for 16 hours at 20° and evaporated to give 6-butyl-1-(4-o-cyanobenzyloxybenzyl)-1,2-dihydro-2-oxopyridine after conventional working-up.

Provenance & Evidence