4'-Fluoroacetophenone → HCID 18996115, compound

HRID 1729377Notes

Reaction equation

F[C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[Br:11][C:12]1[CH:13]=[C:14]([SH:18])[CH:15]=[CH:16][CH:17]=1>>[Br:11][C:12]1[CH:13]=[C:14]([S:18][C:2]2[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=2)[CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 98284'-Fluoroacetophenone

HCID 80597m-Bromobenzenethiol

Product 1

HCID 18996115HCID 18996115, compoundYield 82%

Procedure

Using an analogous procedure to that described in the last paragraph of the portion of Example 66 which is concerned with the preparation of starting materials, 4'-fluoroacetophenone was reacted with 3-bromobenzenethiol to give 4'-(3-bromophenylthio)acetophenone in 82% yield, m.p. 54°-57° C.

Sources & evidence

ORD record: ord-3b4e01335b144393941a0bf3a381ebd0
Source dataset: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05332757

Reaction notes

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