HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(+)-3-(t-butyldimethylsilyloxy)-2-methylpropanal → 3-(1-Oxo-2-(R)-methyl-3-(R)-hydroxy-4-(S)-methyl-5-t-butyldimethylsiloxypentyl)-4-(R)-(phenylmethyl)-2-oxazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(+)-3-(t-butyldimethylsilyloxy)-2-methylpropanal | HCID 10241965 | — |
| Reactant | (R)-(-)-4-Benzyl-3-propionyl-2-oxazolidinone | HCID 10966403 | — |
| Product | 3-(1-Oxo-2-(R)-methyl-3-(R)-hydroxy-4-(S)-methyl-5-t-butyldimethylsiloxypentyl)-4-(R)-(phenylmethyl)-2-oxazolidinone | HCID 53829208 | — |
Reaction Steps
This material is prepared from (R)-3-(1-oxopropyl)-4-(phenylmethyl)-2-oxazolidinone and 2-(S)-methyl-3-t-butyldimethylsiloxypropanal following the method of Evans and Gage, as described in Org. Syn., Vol. 68, 19xx, p. 83.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05332807 |
| Source dataset | uspto-grants-1994_07 |
| ORD ID | ord-f641894474f242d3bf4f1488823031b8 |
| Source note | uspto-grants-1994_07 |