Iodomethyl pivalate → HCID 141573535, compound

Participants

Reaction Steps

Sodium 7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(tetrahydropyran-4-yl)methylthio-3-cephem-4-carboxylate (200 mg) as prepared in Example 31(b) was reacted with iodomethyl pivalate (181 mg) similarly to Example 28 for the esterification reaction. The resulting reaction solution was post-treated and the produced compound was recovered and purified similarly to Example 28 to give the titled compound (120 mg; 51%).

Provenance & Evidence