Iodomethyl pivalate → HCID 141559409, compound

Participants

Reaction Steps

Sodium 7-[(Z)-2-(2-aminothiazol-4-yl)-2-trityloxyiminoacetamido]-3-(1,3-dioxolan-4-yl)methylthio-3-cephem-4-carboxylate (71 mg) as prepared in Example 35(b) was reacted with iodomethyl pivalate (68 mg) similarly to Example 28 for the esterification reaction. The resulting reaction solution was post-treated and the produced compound was recovered and purified similarly to Example 28 to give the titled compound (43 mg; 51%).

Provenance & Evidence