1-(1-Bromoethyl)-3-(trifluoromethyl)benzene → 2-[[2-Amino-5-[1-[3-(trifluoromethyl)phenyl]ethylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol

HRID 172957Notes

Reaction equation

HRID 172957 reaction equation
[Br:20][CH:21]([CH3:22])[c:23]1[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]1.[NH2:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([SH:18])[n:8][c:9]2[NH:10][CH:11]([CH2:12][OH:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[n:19]1>>[NH2:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([S:18][CH:21]([CH3:22])[c:23]3[cH:24][c:25]([C:29]([F:30])([F:31])[F:32])[cH:26][cH:27][cH:28]3)[n:8][c:9]2[NH:10][CH:11]([CH2:12][OH:13])[CH2:14][CH:15]([CH3:16])[CH3:17])[n:19]1

Participants

3

Reactant 2

HCID 27756241-(1-Bromoethyl)-3-(trifluoromethyl)benzeneHCID 178445193HCID 178445193, compound

Product 1

HCID 731552642-[[2-Amino-5-[1-[3-(trifluoromethyl)phenyl]ethylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol

Sources & evidence

ORD record
ord-860eedb8027e445a94efc68ae916ce75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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