HCID 68140243, compound → HCID 68140931, compound

Participants

Reaction Steps

To a solution of benzhydryl 7β-benzyloxycarbonylamino-3β-chloro-3-methylcepham-4α-carboxylate (110 mg) in ethanol (10 ml) is added previously reduced 5% palladium charcoal (50 mg), and the mixture is shaken under hydrogen gas. After 60 minutes, the reaction mixture is filtered, and the filtrate is evaporated. The residue is treated with a mixture of ether and petroleum ether to give solid benzhydryl 7β-amino-3β-chloro-3α-methylcepham-4α-carboxylate (52 mg).

Provenance & Evidence