HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methoxyphenyl)but-3-en-2-one → HCID 12391099, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methoxyphenyl)but-3-en-2-one | HCID 95414 | — |
| Reactant | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 12391099 | HCID 12391099 | 52% |
Reaction Steps
Heating a solution of 17.5 g of 4-methoxybenzylideneacetone and 13.0 g of amidinoacetic acid ethyl ester in 150 ml of ethanol for 2 hours yields 2-amino-6-methyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester of melting point 160°-161°C (ethanol). Yield: 52 percent theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989708 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-12e8f636cc38462cb0102bead05fb21b |
| Source note | uspto-grants-1976_11 |