HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 13077478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-[(1-Phenyl-1H-benzimidazol-2-yl)amino]propan-1-ol | HCID 21500324 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 13077478 | HCID 13077478 | — |
Reaction Steps
Thionyl chloride (10 ml.) was added dropwise to a stirred solution of 2-(3-hydroxypropylamino)-1-phenylbenzimidazole (11.0 g.) in dry chloroform (100 ml.) and the solution heated under reflux for 2 hours. On dilution with ether the title compound crystallised as its hydrochloride (13.06 g., m.p. 176° to 179° C). Found: C, 59.65, H, 5.3, N, 12.95%. C16H16ClN3.HCl requires: C, 59.65, H, 5.3, N, 13.05%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989709 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-87d0e6a5f2a14a8d8f69380166e3bd19 |
| Source note | uspto-grants-1976_11 |