Octanoyl chloride → HCID 21500421, compound

HRID 1729714Notes

Reaction equation

[F:1][C:2]([F:23])([F:22])[C:3]1[CH:21]=[CH:20][C:6]2[O:7][C:8]3[CH:19]=[CH:18][CH:17]=[CH:16][C:9]=3[CH2:10][N:11]([C:12]([NH:14][NH2:15])=[O:13])[C:5]=2[CH:4]=1.C(=O)([O-])[O-].[Na+].[Na+].[C:30](Cl)(=[O:38])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]>>[C:30]([NH:15][NH:14][C:12]([N:11]1[CH2:10][C:9]2[CH:16]=[CH:17][CH:18]=[CH:19][C:8]=2[O:7][C:6]2[CH:20]=[CH:21][C:3]([C:2]([F:1])([F:22])[F:23])=[CH:4][C:5]1=2)=[O:13])(=[O:38])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

Participants

Reactant 3

HCID 8124Octanoyl chloride

HCID 10340Sodium Carbonate

HCID 70606301HCID 70606301, compound

Product 1

HCID 21500421HCID 21500421, compound

Procedure

By substituting equivalent quantities of 8-trifluoromethyl-10,11-dihydrodibenz[b,f][1,4]oxazepine-10-carboxylic acid hydrazide, sodium carbonate and octanoyl chloride in the procedure of Example 1, there is obtained 1-octanoyl-2-(8-trifluoromethyl-10,11-dihydrodibenz[b,f][1,4]oxazepine-10-carbonyl)hydrazine, which melts at about 97°-100° and is represented by the following structural formula ##SPC4##

Sources & evidence

ORD record: ord-34f8717e31344d219431bc59917c3cb0
Source dataset: uspto-grants-1976_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03989719

Reaction notes

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