HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-Ethyl-2-(3,5-di-tert.butyl-4-hydroxyphenyl)-1-nitroethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Nitropropane | HCID 7903 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3,5-Di-t-butyl-4-hydroxy-benzylpyridinium chloride | HCID 10496903 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Ethyl-2-(3,5-di-tert.butyl-4-hydroxyphenyl)-1-nitroethane | HCID 20322381 | 98% |
Reaction Steps
A solution of 16.7 grams of 3,5-di-tert.butyl-4-hydroxybenzylpyridinium chloride in 50 milliliters of ethanol was added dropwise in 15 minutes to a slurry of 2.0 grams of sodium hydroxide and 13.4 grams of 1-nitropropane (200% excess) in 50 milliliters of ethanol. The reaction mixture as stirred for 3 hours and was then poured into 600 milliliters of water. The oil which precipitated was separated by extraction with hexane. The extract was evaporated to give 15.0 grams (98% of theory) of 1-ethyl-2-(3,5-di-tert.butyl-4-hydroxyphenyl)-1-nitroethane which melted at 55°-60° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989738 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-b8898968e2e446f3a77f5ffb442e79bf |
| Source note | uspto-grants-1976_11 |