Benzoyl chloride → HCID 53979616, compound

HRID 1729764Notes

Reaction equation

HRID 1729764 reaction equation
[CH2:1]([O:4][NH:5][C:6](=[C:9]1[C:18](=[O:19])[CH2:17][CH:16]2[CH:11]([CH2:12][CH2:13][CH2:14][CH2:15]2)[C:10]1=[O:20])[CH2:7][CH3:8])[CH:2]=[CH2:3].[OH-].[Na+].[C:23](Cl)(=[O:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>CC(C)=O.O>[CH2:1]([O:4][N:5]=[C:6]([C:9]1[C:10](=[O:20])[CH:11]2[CH:16]([CH2:15][CH2:14][CH2:13][CH2:12]2)[CH2:17][C:18]=1[O:19][C:23](=[O:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[CH2:7][CH3:8])[CH:2]=[CH2:3]

Participants

6

Reactant 3

HCID 7412Benzoyl chlorideHCID 14798Sodium HydroxideHCID 178460135HCID 178460135, compound

Product 1

HCID 53979616HCID 53979616, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

To a solution of 2-(1-allyloxyaminopropylidene)decaline-1,3-dione (2 g) in acetone (30 ml), sodium hydroxide (0.2 g) in water (1 ml) was added at room temperature and then benzoylchloride (0.7 g) was added. After stirring for 5 hours, the reaction mixture was poured into ice-water and extracted with chloroform. The extract was washed with one normal sodium hydroxide and dried over magnesium sulfate. The solvent was removed in vacuo and an oily substance (1.8 g) was obtained.

Workup

  1. extractionextracted with chloroform
  2. washThe extract was washed with one normal sodium hydroxide
  3. dry with materialdried over magnesium sulfate
  4. customThe solvent was removed in vacuo
  5. customan oily substance (1.8 g) was obtained

Sources & evidence

ORD record
ord-0e1d636e72b04e04b03b9ed5684e7596
Source dataset
uspto-grants-1976_11
Patent number
US03989737

Reaction notes

Loading…