Sodium Hydroxide → HCID 86734120, compound

HRID 1729765Notes

Reaction equation

HRID 1729765 reaction equation
[CH2:1]([O:4][NH:5][C:6](=[C:9]1[C:14](=[O:15])[CH2:13][C:12]2([CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[CH2:11][C:10]1=[O:21])[CH2:7][CH3:8])[CH:2]=[CH2:3].[OH-:22].[Na+]>CC(C)=O.O>[CH2:1]([O:4][N:5]=[C:6]([C:9]1[C:14](=[O:15])[CH2:13][C:12]2([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[CH2:11][C:10]=1[O:21][C:6](=[O:22])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:7][CH3:8])[CH:2]=[CH2:3]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 178460136HCID 178460136, compound

Product 1

HCID 86734120HCID 86734120, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

To a solution of 4-(1-allyloxyaminopropylidene)spirobicyclohexane-3,5-dione (1.5 g) in acetone (30 ml), sodium hydroxide (0.2 g) in water (1 ml) was added at room temperature and then benzoylochloride (0.7 g) was added. After stirring for 5 hr, the reaction mixture was poured into ice-water and extracted with chloroform. The extract was washed with one normal sodium hydroxide and dried over magnesium sulfate. The solvent was removed in vacuo and oily substance (0.8 g) was obtained.

Workup

  1. additionwas added
  2. extractionextracted with chloroform
  3. washThe extract was washed with one normal sodium hydroxide
  4. dry with materialdried over magnesium sulfate
  5. customThe solvent was removed in vacuo
  6. customoily substance (0.8 g) was obtained

Sources & evidence

ORD record
ord-958c953b86bc484b8876c0011bbb58eb
Source dataset
uspto-grants-1976_11
Patent number
US03989737

Reaction notes

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