2-Butanone, 4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]- → HCID 21274350, Verbindung

HRID 1729767Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1729767
[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][CH2:17][C:18](=[O:20])[CH3:19])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Cr]([O-])([O-])=O.[Cu+2]>[C:12]([C:9]1[CH:8]=[C:7]([CH2:16][CH2:17][CH:18]([OH:20])[CH3:19])[CH:6]=[C:5]([C:1]([CH3:3])([CH3:2])[CH3:4])[C:10]=1[OH:11])([CH3:15])([CH3:13])[CH3:14]

Komponenten

4

Edukt 1

HCID 39609622-Butanone, 4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-

Produkt 1

HCID 21274350HCID 21274350, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178505374HCID 178505374, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

4-(3,5-di-t-butyl-4-hydroxyphenyl) butane-2-ol was prepared by catalytic hydrogenation of 84.8 grams of 4-(3,5-di-t-butyl-4-hydroxyphenyl) butane-2-one in 400 milliliters of ethanol solvent in the presence of 10 grams of copper chromite catalyst at 150° C, and 1000 pounds per square inch pressure in a one-liter autoclave. Reduction was complete in three hours. The catalyst was filtered off and the filtrate was evaporated. The residue was crystallized by the addition of hexane to yield 82.9 grams of a white solid product (97 percent yield) having a melting point between 64° and 66° C.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated
  3. customThe residue was crystallized by the addition of hexane

Quellen und Nachweise

ORD-Eintrag
ord-a0a7db1cb6dc4e49a29c7100a3a439b6
Quelldatensatz
uspto-grants-1976_11
Patentnummer
US03989741

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