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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172982Generated: October 26, 2026

Tetrahydrofuran → 5-Bromo-2-(2,6-difluoro-4-methoxyphenyl)pyrimidine

https://huagongshe.com/reaction/172982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant3,5-DifluoroanisoleHCID 2724518—
Reactant5-Bromo-2-iodopyrimidineHCID 7006651—
ReactantButyllithiumHCID 178418339—
ReactantHCID 178420554HCID 178420554—
Product5-Bromo-2-(2,6-difluoro-4-methoxyphenyl)pyrimidineHCID 67394249—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-02e231ed2f784de0b909e95b4468f92f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)