1,2-Ethanediamine, N1,N1,N2-trimethyl- → HCID 21455958, compound

Participants

Reaction Steps

0.65 g. 3-(1-methyl-2-nitro-5-imidazolyl)-6-chloro-s-triazolo[4,3-b]pyridazine were reacted in 13 ml. dimethyl formamide with 0.5 g. trimethylethylenediamine at 60° C. for 15 minutes. After working up the reaction mixture in a manner analogous to that described in Example 47, there was obtained 0.6 g. (75 percent of theory) of the desired 3-(1-methyl-2-nitro-5 -imidazolyl)-6-[N-methyl-N-(β-dimethyl-aminoethyl)-amino] -s-triazolo[4,3-b]pyridazine in the form of yellow crystals which have a melting point of 196° - 198° C.

Provenance & Evidence