HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21406503, compound → (+-)-Cicloprofen
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21406503 | HCID 21406503 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (+-)-Cicloprofen | HCID 37589 | 99.2% |
Reaction Steps
A solution of α-methylenefluorene-2-acetic acid (2.6g.) in dioxane (50ml.) is hydrogenated in the presence of 5% palladium on charcoal (800mg.). The mixture is filtered and the filtrate evaporated to dryness. The residue is sublimed to afford the title compound (2.6g.). The analytical sample is prepared by recrystallization from aqueous methanol, mp 180°-182°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989841 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-63827fc808b24e46b2f27f96477644f4 |
| Source note | uspto-grants-1976_11 |