Potassium Hydroxide → HCID 21406514, compound

HRID 1729901Notes

Reaction equation

HRID 1729901 reaction equation
C[C:2]1[C:14]2[CH2:13][C:12]3[C:7](=[CH:8][CH:9]=[C:10]([O:15][CH3:16])[CH:11]=3)[C:6]=2[CH:5]=[CH:4][C:3]=1[CH2:17][C:18]([OH:20])=[O:19].[OH-].[K+]>C(O)C>[CH3:16][O:15][C:10]1[CH:11]=[C:12]2[C:7]([C:6]3[CH:5]=[CH:4][C:3]([CH2:17][C:18]([OH:20])=[O:19])=[CH:2][C:14]=3[CH2:13]2)=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 70633583HCID 70633583, compound

Product 1

HCID 21406514HCID 21406514, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 20mg. of methyl 7 -methoxyfluorene-2-acetic acid in 7ml. of ethanol containing 0.5ml. of 50% aqueous potassium hydroxide solution is refluxed overnight. The mixture is acidified and the solid collected by filtration. Crystallization from chloroform-isopropyl ether gives 8mg. of the title compound, mp 200°-202°. The analytical sample is prepared by tube to tube evaporative distillation, mp 203°-205°; λKBr 5.93μ.

Workup

  1. filtrationthe solid collected by filtration
  2. customCrystallization from chloroform-isopropyl ether
  3. customgives 8mg

Sources & evidence

ORD record
ord-8754e90c56044f8fb76237284e7648dd
Source dataset
uspto-grants-1976_11
Patent number
US03989841

Reaction notes

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