HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-acetoxynonane → 7-[1-(4-Hydroxy-2-nonynyl)ureido]heptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-acetoxynonane | HCID 13104716 | — |
| Reactant | 1-Bromo-4-acetoxy-2-nonyne | HCID 20386120 | — |
| Reactant | ethyl 7-[N-(4-acetoxy-2-nonynyl)cyanamido]heptanoate | HCID 86734140 | — |
| Product | 7-[1-(4-Hydroxy-2-nonynyl)ureido]heptanoic acid | HCID 21501436 | — |
Reaction Steps
The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-bromo-4-acetoxy-2-nonyne (Example I, Step 3). The product of Step A is thus ethyl 7-[N-(4-acetoxy-2-nonynyl)cyanamido]heptanoate. The subsequent steps yield 7-[N-(4-hydroxy-2-nonynyl)cynamido]heptanoic acid (B), and 7-[1-(4-hydroxy-2-nonynyl)ureido]heptanoic acid (C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989749 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-76b38dea4bcc47c4911df1a52b412615 |
| Source note | uspto-grants-1976_11 |