HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-methyl-7-iodoheptanoate → 7-[1-(4(R)-hydroxy-2-nonynyl)ureido]heptanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-methyl-7-iodoheptanoate | HCID 20322201 | — |
| Reactant | Ethyl 7-bromo-2-methylheptanoate | HCID 22770549 | — |
| Reactant | methyl 7-[N-(4-acetoxynonyl)cyanamido]-3-methylheptanoate | HCID 86734146 | — |
| Product | 7-[1-(4(R)-hydroxy-2-nonynyl)ureido]heptanoic acid | HCID 22794232 | — |
| Product | 7-[N-(4-(R)-hydroxy-2-nonynyl)cyanamido]heptanoic acid | HCID 86734141 | — |
Reaction Steps
The synthesis of this compound is carried out as described in Example 7 except that, in Step A, the ethyl 7-bromo-2-methylheptanoate is replaced by an equimolar amount of methyl 3-methyl-7-iodoheptanoate. The product of Step A is thus methyl 7-[N-(4-acetoxynonyl)cyanamido]-3-methylheptanoate. The subsequent steps yield 7-[N-(4-hydroxynonyl)cyanamido]-3-methylheptanoic acid (B) and 7-[1-(4-hydroxynonyl)ureido]-2-methylheptanoic acid (C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03989749 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-eb76f882de1847ebb7f271eeef2b7e50 |
| Source note | uspto-grants-1976_11 |