1-Chloro-4-acetoxynonane → HCID 86734147, compound

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Reaction Steps

The synthesis of this compound is carried out initially as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-chloro-4-acetoxy-8-methylnonane (Example B, Step 3). The product of Step A is thus ethyl 7-[N-(4 -acetoxy-8-methylnonyl)cyanamido]heptanoate. The hydrolysis (Step B) affords 7-[N-(4-hydroxy-8-methylnonyl)cyanamido]-heptanoic acid. This product is then treated as described in Example 3, Step A, to yield the subject compound 7-[N-(4-hydroxy-8-methylnonyl)thioureido]heptanoic acid.

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