反应详情

The synthesis of this compound, initially, is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-chloro-4-acetoxyundecane (Example C, Step 3 ). The product of Step A is thus ethyl 7-[N-(4-acetoxyundecyl)cyanamido]heptanoate. The subsequent steps yield 7-[N-(4-hydroxyundecyl)cyanamido]heptanoic acid (B). This product then is treated as described in Example 3, Step A, to yield the subject compound 7-[1-(4-hydroxyundecyl)thioreido]heptanoic acid.

1. customThe synthesis of this compound