Bromine → HCID 178465859, compound

Participants

Reaction Steps

To a stirred suspension of 343 g. (1.57 mol.) of 2-acetyl-3-methylquinoxaline 1,4-dioxide in 3,000 ml. of methanol was added (1.74 mole) of bromine over a period of 2 hours. The reaction mixture was then stirred for 5 days at room temperature. The resulting yellow solid was collected by suction filtration, washed with methanol and ether, and dried to give 331 g. (71% yield) of 2-acetyl-3-bromomethylquinoxaline 1,4-dioxide, m.p. 164°-166° C.

Provenance & Evidence