Diisobutylaluminumhydride → HCID 21404785, compound

Participants

Reaction Steps

To 1 part of methyl 3-methoxy-2-azanaphthaleneacetate in 25 parts by volume of toluene at -78° C is slowly added 0.33 part of diisobutylaluminum hydride in toluene. The reaction is stirred for 1 hour and allowed to come to room temperature. The reaction is quenched with ethylacetate followed by ice water. The organic layer is washed with saturated sodium chloride, dried with anhydrous sodium sulfate, and 3-methoxy-2-azanaphthaleneacetaldehyde is isolated. This compound has the following structural formula ##SPC24##

Provenance & Evidence