Acrylamide, N-cyclohexyl- → N-Cyclohexyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

HRID 1730002Notes

Reaction equation

HRID 1730002 reaction equation
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[CH:15]1([NH:21][C:22](=[O:25])[CH:23]=[CH2:24])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH:15]1([NH:21][C:22](=[O:25])[CH2:23][CH2:24][N:11]2[CH2:12][CH2:13][C:14]3=[C:2]([CH3:1])[C:3]4[C:8]([CH:9]3[CH2:10]2)=[CH:7][CH:6]=[CH:5][CH:4]=4)[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 137811Acrylamide, N-cyclohexyl-HCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

Product 1

HCID 54100677N-Cyclohexyl-3-(1,3,4,9b-tetrahydro-5-methyl-2H-indeno [1,2-c]pyridin-2-yl) propionic acid amide

Procedure

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and N-cyclohexyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 8 hours. M.P. of the title compound 162.5°-163.5° from acetone.

Workup

  1. customReaction period 8 hours

Sources & evidence

ORD record
ord-6b9ecf93856348e7b6719dc4e1211dc4
Source dataset
uspto-grants-1976_11
Patent number
US03991066

Reaction notes

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