Diethylamine → HCID 86734158, compound

Participants

Reaction Steps

trans-5-Ethoxycarbonyl-3-(5-nitrofur-2-ylvinyl)-1,2,4-oxadiazole (332 mg.) was heated under reflux with diethylamine (5 ml.) for 30 min. to give a deep red solution. Evaporation gave a red solid; recrystallisation from methanol (3 ml.) gave trans-5-diethylcarbamoyl-3-(5-nitrofur-2-ylvinyl)1,2,4-oxadiazole (208 mg., 57%), m.p. 118°-119°, λmax. (EtOH) 240 and 349 nm. (ε18,600 and 19,900), νmax. (CHBr3) 1665 (CONEt2), 1510, 1352 (NO2) and 960 cm.-1 (trans CH=CH).

Provenance & Evidence