Maleic Acid → HCID 5384562, compound

Participants

Reaction Steps

A mixture of 5.54 g. (0.02 mole) 10-(2-dimethylaminoethyl)-10,11-dihydro-5-methylene-5H-dibenzo[a,d]cycloheptene and 0.6 g 5% palladium on carbon in 60 ml. ethanol is hydrogenated at atmospheric pressure and room temperature. The hydrogenation is stopped after 1 equivalent of hydrogen is absorbed, the catalyst is removed by filtration and the filtrate concentrated to a small volume in vacuo. The concentrated filtrate is treated with 2.32 g. (0.02 mole) maleic acid in ethanol and the resulting solid is filtered and washed with cold ethanol to give 10,11-dihydro-10-(2-dimethylaminoethyl)-5-methyl-5H-dibenzo[a,d]cycloheptene maleate, m.p. 120°-122° C.

Provenance & Evidence