HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 1-Phenylpyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Gamma-Butyrolactone | HCID 7302 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Phenylpyrrolidin-2-one | HCID 78375 | 39.1% |
Reaction Steps
9.3 g (0.1M) aniline and 9.5 g (0.11M) γ-butyrolactone were mixed and heated to 200° for 48 hours. The mixture was then placed under high vacuum whereupon unreacted γ-butyrolactone, analine and water were removed. Distillation of the residue at 138°-140°/300 μ gave 6.3 g (39%) of the product. [84% yield, based on reclaimed starting materials.]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03991203 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-dae19243f1984b94acbf76a14b01e2ab |
| Source note | uspto-grants-1976_11 |