Dimetridazole → HCID 12214395, compound

HRID 1730177Notes

Reaction equation

HRID 1730177 reaction equation
[CH2:1]([N:3]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][N:5]=[C:4]1[CH3:11])[CH3:2].CN1C([N+]([O-])=[O:19])=CN=C1C>>[CH2:1]([N:3]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][N:5]=[C:4]1[CH:11]=[O:19])[CH3:2]

Participants

3

Reactant 2

HCID 3090DimetridazoleHCID 12228871HCID 12228871, compound

Product 1

HCID 12214395HCID 12214395, compound

Procedure

With regard to the dimethylamino compound, said compound is prepared by employing the procedure set forth in Example 3, with the exception that 1-ethyl-2-methyl-5-nitroimidazole is utilized instead of 1,2-dimethyl-5-nitroimidazole. The process yields 1-ethyl-5-nitro-2-imidazolecarboxaldehyde, 4',4'-dimethyl-3'-thiosemicarbazone, which is cyclized as in Example 3 to 2-(2-dimethylamino-5-thiadiazoly)- 1-ethyl-5-nitroimidazole.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-d632f3d6a550420796d0c82a5119ec46
Source dataset
uspto-grants-1976_11
Patent number
US03991200

Reaction notes

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