Acetone Cyanohydrin → 1-Aminocyclohexanecarbonitrile
Reaction equation
[CH2:1]1[CH2:6][CH2:5][C:4](O)([C:7]#[N:8])[CH2:3][CH2:2]1.CC(C)(O)C#[N:13]>>[NH2:13][C:4]1([C:7]#[N:8])[CH2:5][CH2:6][CH2:1][CH2:2][CH2:3]1Participants
3
Procedure
In a similar manner, 1-aminoisobutyronitrile was prepared by substituting for cyclohexanone cyanohydrin an equivalent amount of acetone cyanohydrin.
Sources & evidence
- ORD record
- ord-a4bedcf01e744b1ca29b1b36c001693f
- Source dataset
- uspto-grants-1976_11
- Patent number
- US03992351
Reaction notes
Loading…