Sodium borohydride → HCID 21405704, compound

HRID 1730290Notes

Reaction equation

HRID 1730290 reaction equation
[BH4-].[Na+].C([O:6][C:7]1[CH:12]=[CH:11][C:10]([N:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[C:16](=[O:23])[CH2:15][CH2:14]2)=[CH:9][CH:8]=1)(=O)C>>[OH:6][C:7]1[CH:8]=[CH:9][C:10]([N:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH:16]([OH:23])[CH2:15][CH2:14]2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 21405730HCID 21405730, compound

Product 1

HCID 21405704HCID 21405704, compound

Procedure

Conventional sodium borohydride reduction of compound A [method see Example 2c), below] yields 1-p-hydroxyphenyl-4-hydroxy-1,2,3,4-tetrahydro-quinoline.

Sources & evidence

ORD record
ord-e14b2fcbd42c4fc9838d5808c4d6a79a
Source dataset
uspto-grants-1976_11
Patent number
US03992386

Reaction notes

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