Chloroform → HCID 54205117, compound

HRID 1730307Notes

Reaction equation

HRID 1730307 reaction equation
[C:1]1([N:7]2[C:11](=[NH:12])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:16]=[CH:17][C:18]([Cl:21])([Cl:20])[Cl:19].C(Cl)(Cl)[Cl:23]>>[C:1]1([N:7]2[C:11](=[N:12][C:17]([OH:16])([Cl:23])[C:18]([Cl:21])([Cl:20])[Cl:19])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 6407ChloralHCID 214974605-Imino-3-methyl-1-phenylimidazolidine-2,4-dione

Product 1

HCID 54205117HCID 54205117, compound

Conditions

Temperature
20 °C

Procedure

1-phenyl-3-methyl-5-iminoimidazolidine-2,4-dione (15.0 g -- 0.074 mol) was slurried in 40 ml chloroform. Chloral (21.8 g -- 0.148 mol) was added directly to the slurry. Exothermicity raised the temperature 20° C.The reaction mixture was momentarily homogeneous before an abundance of product precipitated. An additional 100 ml of chloroform was added at thispoint. After 0.5 hour the mixture was filtered. The filter cake was washed with chloroform and dried. The product melted at 130°-133° C.

Workup

  1. customprecipitated
  2. additionAn additional 100 ml of chloroform was added at thispoint
  3. filtrationAfter 0.5 hour the mixture was filtered
  4. washThe filter cake was washed with chloroform
  5. customdried

Sources & evidence

ORD record
ord-219a48721f5f443cb6d2e9a182aef157
Source dataset
uspto-grants-1976_11
Patent number
US03992402

Reaction notes

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