HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-Formylpropionate → 4-Methyl-1-(3,4-dichlorobenzyl)-pyrazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-Formylpropionate | HCID 10898741 | — |
| Reactant | (3,4-Dichlorobenzyl)hydrazine | HCID 20495842 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Methyl-1-(3,4-dichlorobenzyl)-pyrazol-5-one | HCID 23334400 | — |
Reaction Steps
10.9 g of 3,4-dichlorobenzylhydrazine were added dropwise to a solution of 7.5 g of α-formylpropionic acid ethyl ester in 50 ml of ethanol. After stirring overnight at room temperature, the solvent was distilled off in vacuo and the solid residue was recrystallized from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03992404 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-ab67eeb6a9b1431794ec7be3c49ad905 |
| Source note | uspto-grants-1976_11 |