4-Methylbenzoyl Chloride → HCID 561726, compound

HRID 1730345Notes

Reaction equation

HRID 1730345 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][CH:11]([NH2:14])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](Cl)=[O:21])=[CH:18][CH:17]=1>>[CH2:1]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:20](=[O:21])[C:19]2[CH:23]=[CH:24][C:16]([CH3:15])=[CH:17][CH:18]=2)[CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 134054-Methylbenzoyl ChlorideHCID 4158521-Benzyl-4-piperidylamine

Product 1

HCID 561726HCID 561726, compound

Procedure

The 1-benzyl-4-aminopiperidine prepared in Example 30 was treated with p-methylbenzoyl chloride in a similar manner to that described in the sameexample and the product converted to a salt.

Sources & evidence

ORD record
ord-c14f8d92a76e402c8dffa3f453e95db0
Source dataset
uspto-grants-1976_11
Patent number
US03992389

Reaction notes

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