HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-4-Piperidylbenzamide → 2-(4-Benzamidopiperidino)ethylhydroxymethyl ketone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-4-Piperidylbenzamide | HCID 118120 | — |
| Reactant | Hydroxymethylvinyl ketone | HCID 12369703 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(4-Benzamidopiperidino)ethylhydroxymethyl ketone | HCID 86734193 | — |
Reaction Steps
4-Benzamidopiperidine (2.4 g.) in ethanol (15 ml.) was added to hydroxymethylvinyl ketone (2.0 g.). An exothermic reaction occured and crystallisation occurred on cooling to give 2-(4-benzamidopiperidino)ethylhydroxymethyl ketone, m.p. 154°-155° C. (Found: C, 65.9; H, 7.7; N, 9.5; C16H22N2O3 requires C, 66.2; H, 7.6; N, 9.65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03992389 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-0b7730f399e14c219eceeba3421a8519 |
| Source note | uspto-grants-1976_11 |