2-Bromo-4,6-difluoroanisole → (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(3,5-difluoro-2-methoxy-phenyl)-methanone

HRID 173045Notes

Reaction equation

HRID 173045 reaction equation
[Br:17][c:18]1[c:19]([O:26][CH3:27])[c:20]([F:25])[cH:21][c:22]([F:24])[cH:23]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[CH3:16]>>[C:4](=[O:5])([c:6]1[c:7]([NH2:15])[n:8][c:9]([S:12][CH2:13][CH3:14])[n:10][cH:11]1)[c:18]1[c:19]([O:26][CH3:27])[c:20]([F:25])[cH:21][c:22]([F:24])[cH:23]1

Participants

3

Reactant 2

HCID 27362632-Bromo-4,6-difluoroanisoleHCID 119748325-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-

Product 1

HCID 21070578(4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(3,5-difluoro-2-methoxy-phenyl)-methanone

Sources & evidence

ORD record
ord-f340c0b523ca40048526af1830ccc5d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…