Potassium Hydroxide → 2-(o-Chlorobenzyl)-4-nitroaniline

HRID 1730460Notes

Reaction equation

HRID 1730460 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][C:3]=1[C:4](=NN)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11].[OH-].[K+]>C(O)COCCO>[Cl:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[CH2:4][C:3]1[CH:14]=[C:15]([N+:18]([O-:20])=[O:19])[CH:16]=[CH:17][C:2]=1[NH2:1]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 867330932-Amino-2'-chloro-5-nitrobenzophenone hydrazone

Product 1

HCID 214973642-(o-Chlorobenzyl)-4-nitroaniline

Reagents, catalysts & solvents 1

HCID 8117Diethylene GlycolSolvent

Procedure

In the manner given in Preparation 11, 2-amino-2'-chloro-5-nitrobenzophenone hydrazone is refluxed with potassiumhydroxide in diethylene glycol to give 2-(o-chlorobenzyl)-4-nitroaniline.

Sources & evidence

ORD record
ord-f9f70b3016044957b83bbc447291ee4b
Source dataset
uspto-grants-1976_11
Patent number
US03992400

Reaction notes

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