HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminoacetaldehyde → 1-(alpha-Phenyl-o-tolyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminoacetaldehyde | HCID 363 | — |
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Reactant | 2-Benzylaniline | HCID 119805 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 1-(alpha-Phenyl-o-tolyl)imidazole | HCID 21497358 | — |
Reaction Steps
In the manner given in Example 1, α-phenyl-o-toluidine is reacted first with trimethyl orthoformate; the resulting product is reacted with aminoacetaldehyde, dimethyl acetal, and the resulting product of this reaction is heated with titanium tetrachloride in monoglyme to give 1-(α-phenyl-o-tolyl)imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03992400 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-81a992cc110d4c3ca100eaea71f2ca7d |
| Source note | uspto-grants-1976_11 |